支气管肺泡灌洗大剂量氨溴索治疗急性肺脓肿的临床效果观察

在线阅读 下载PDF 导出详情
摘要    [摘要 ] 目的 研究分析支气管肺泡灌洗大剂量氨溴索治疗急性肺脓肿的效果。 方法 此次研究的对象是选择 2018年 1月~ 2020年 1月收治的急性肺脓肿患者 120例,将其临床资料进行回顾性分析,并按随机数字表法分为大剂量氨溴索灌洗 60例(治疗组)和生理盐水灌洗 60例(对照组),两组均每周灌洗 2次,疗程 2~ 4周,于治疗后 4周复查胸部 CT。 结果 治疗组治愈率为 95%,明显高于对照组治愈率 40%,治疗组灌洗次数 [( 4.3±1.3)次 ]较对照组灌洗次数 [( 5.4±1.4)次 ]明显减少,治疗组抗菌药疗程 [( 16.2±2.7) d]较对照组抗菌药疗程 [( 24.8±3.1) d]明显缩短,治疗组住院时间 [( 17.8±4.3) d]较对照组住院时间 [( 25.3±3.5) d]明显缩短,差异有高度统计学意义( P < 0.01)。 结论 支气管肺泡灌洗大剂量氨溴索治疗急性肺脓肿是一种很好的治疗手段。      [关键词 ] 支气管肺泡灌洗;氨溴索;急性肺脓肿;治疗     [Abstract] Objective To study and analyze the effect of large dose ambroxol in the treatment of acute lung abscess. Methods 120 patients with acute lung abscess admitted from January 2018 to January 2020 were selected for this study. The clinical data were analyzed retrospectively. According to the random number table method, they were divided into 60 patients (treatment group) with high-dose ambroxol and 60 patients (control group) with normal saline. The two groups were lavaged twice a week for 2-4 weeks. Chest CT was reexamined four weeks after treatment. result The cure rate of the treatment group was 95%, which was significantly higher than that of the control group by 40%. The number of lavage times in the treatment group [(4.3 ± 1.3) times] was significantly reduced compared with that in the control group [(5.4 ± 1.4) times], the duration of antibacterial treatment in the treatment group [(16.2 ± 2.7) D] was significantly shorter than that in the control group [(24.8 ± 3.1) D], and the duration of hospitalization in the treatment group [(17.8 ± 4.3) D] was significantly shorter than that in the control group [(25.3 ± 3.5) D] The difference was statistically significant (P < 0.01). Conclusion bronchoalveolar lavage with high dose ambroxol is a good treatment for acute lung abscess.
出处 《中华医学信息导报》 2020年08期
关键词
出版日期 2020年08月11日(中国期刊网平台首次上网日期,不代表论文的发表时间)