摘要
【摘要】 目的：探讨老年痴呆患者接受盐酸多奈哌齐治疗的效果，为临床治疗提供参考依据。 方法： 2018年 1月至 2020年 1月我院对老年痴呆患者 72例进行了分析研究，将患者分成了对照组和实验组，均有 36例，对照组患者接受常规治疗，实验组患者接受常规治疗和盐酸多奈哌齐治疗，对两组的效果和不良反应情况进行了对比分析。 结果：实验组有 18例显效，占总数的 50%， 16例有效，占总数的 44.4%， 2例无效，占总数的 5.56%，有效率是 94.44%，对照组有 15例显效，占总数的 41.76%， 13例有效，占总数的 36.11%， 8例无效，占总数的 22.22%，有效率是 77.78%，实验组有效率比对照组高（ P<0.05）。实验组有 3例不良反应病例，发生率是 8.33%;对照组有 5例不良反应病例，发生率是 13.89%，实验组的不良反应率比对照组低，结果无统计学差异性（ P>0.05）。 结论：老年痴呆患者接受盐酸多奈哌齐治疗的效果突出，患者的不良反应率低，身体受到的伤害比较小，临床中可以进行推广使用。
【关键词】 盐酸多奈哌齐 ;老年痴呆 ;疗效 ;研究
[Abstract] Objective: To explore the effect of donepezil hydrochloride in the treatment of Alzheimer's disease, and to provide reference for clinical treatment. Methods: from January 2018 to January 2020, 72 patients with Alzheimer's disease were analyzed and studied in our hospital. The patients were divided into control group and experimental group, with 36 cases in each group. The patients in the control group received routine treatment, while the patients in the experimental group received routine treatment and donepezil hydrochloride treatment. The effects and adverse reactions of the two groups were compared and analyzed. Results: 18 cases were effective in the experimental group, accounting for 50% of the total, 16 cases were effective, accounting for 44.4% of the total, 2 cases were ineffective, accounting for 5.56% of the total, the effective rate was 94.44%, 15 cases were effective in the control group, accounting for 41.76%, 13 cases were effective, accounting for 36.11% of the total, 8 cases were ineffective, accounting for 22.22% of the total, the effective rate was 77.78%, and the effective rate in the experimental group was higher than that in the control group (P < 0.05). There were 3 cases of adverse reactions in the experimental group, the incidence was 8.33%; there were 5 cases of adverse reactions in the control group, the incidence was 13.89%. The adverse reactions in the experimental group were lower than that in the control group, the results showed no statistical difference (P > 0.05). Conclusion: the effect of donepezil hydrochloride in the treatment of Alzheimer's disease is outstanding, the adverse reaction rate of patients is low, the body injury is relatively small, and it can be used in clinical.
出版日期
2020年06月15日（中国期刊网平台首次上网日期，不代表论文的发表时间）
