摘要
摘要目的探讨来氟米特治疗活动性强直性脊柱炎的疗效及安全性.方法本文选取我院于２０１４年０１月~２０１５年０５月收治的５４例活动性强直性脊柱炎患者,将其随机分为治疗组和对照组,对照组采用甲氨蝶呤治疗,治疗组采用来氟米特治疗,对比两组患者的临床疗效和用药情况结果.结果治疗组１例患者转氨酶升高,停止治疗,１例患者血压明显升高,不良反应发生率为７．４１％,对照组１例患者转氨酶升高,停止治疗,１例患者血压明显升高,１例患者脱发,１例患者口腔溃疡,１例患者白细胞明显减少,停止治疗,不良反应发生率为１８．５２％,两组结果对比存在显著性差异(P＜０．０５),具有统计学意义.结论活动性强直性脊柱炎患者采用来氟米特治疗后,可以明显提升治疗效果,减少不良反应发生率.关键词探讨;来氟米特;活动性强直性脊柱炎;疗效;安全性Abstractobjectivetoexplorethediagnosisandtreatmenttofluorine,curativeeffectandsafetyofactiveankylosingspondylitis．MethodthisarticleselectsthehospitalinJanuＧary,２０１５toMay２０１４treated５４casesofactiveankylosingspondylitispatients,whichwererandomlydividedintotreatmentgroupandcontrolgroup,controlgroupusingmethotrexatetherapy,treatmentgroupfromthetreatment,comparedtwogroupsofpatientswiththeclinicaloutcomeanddrugutilizationresults．Resultstreatmentgroup１patientstransaminaseeleations,stoptreatment,１caseofpatientswithelevatedbloodpressuresignificantly,theincidenceofadversereactionswas７．４１％,controlgroup１paＧtientstransaminaseeleations,stoptreatment,１caseofpatientswithelevatedbloodpressuresignificantly,１caseofpatientswithalopecia,１caseofpatientswithoralcavityulＧc(er,１caseswithwhitebloodcellsdecreasedsignificantly,stoptreatment,theincidenceofadversereactionswas１８．５２％,theresultsoftwogroupshavesignificantdifferenceP＜０．０５),withstatisticalsignificance．Conclusionactiveankylosingspondylitispatientsfromusingspecialtreatment,cansignificantlyimprovecurativeeffect,reducetheinciＧdenceoKfeaydwveorrsdesreactions．toinvestigate;Frommilt;Activeankylosingspondylitis．Curativeeffect;security中图分类号R５９３．２文献标识码B文章编号１００８－６３１５(２０１５)１２－０９８６－０１
出版日期
2015年12月22日（中国期刊网平台首次上网日期，不代表论文的发表时间）
