摘要
Ithabeenknownforsometimethatsometumourshavetheabilitytoproducaehormones.Thishastraditionallybeentermed‘ectopic'hormoneproduction,butwiththeincreasingsensitivityofmodenmoleculartechniques,ithasbecomeclearthatthisisamisnomer;manytissuescanproducehormoner,andnormallydosoatlowlevels,thehormonesactinglocallyascytokinesinaparacrinemanner.Intumours,bymechanismsthatremainunclear,productionofthesehormonesand/orincompletelyprocessedprecursorsisinereased,andthetem‘eutopic’productionismoreappropriate.
出版日期
2002年05月15日(中国期刊网平台首次上网日期,不代表论文的发表时间)