Biovars and Serotypes of Ureaplasma Urealyticum among Chinese Women Undergoing Routine Gynecologic Exam, Women with Sexually Transmitted Infections, and Female Sex Workers

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摘要 Objectives:TocharacterizethedistributionpatternofbiovarsandserotypesofUreaplasmaurealyticuminnormalhealthywomen,sexuallytransmittedinfectionsclinicclients,andinsexworkers.Methods:Weculturedcervicalswabstakenfrom261physicalcheck-upclients,599STIclinicoutpatientsand98sexworkersusingcommercialselectivemedium.SomepositivecultureswerefurtherbiotypedandserotypedbyPCR.Results:(1)U.urealyticumismorecommonlyisolatedinsexworkers(90.8%)thaninthephysicalcheck-upgroup(60.9%)ortheSTIoutpatientgroup(61.3%)(P<0.001).(2)Biovar1ofU.urealyticum(95.0%),especiallysingleinfectionofserotype1,3,and6ofbiovar1,iscommonlyfoundinhealthywomen.(3)Biovar2infectionofU.urealyticumismoreprevalentinsexworkers(28.1%)andSTIoutpatientsgroup(26.6%)thanthatinthephysicalcheck-upgroup(4.9%)(P<0.001).(4)MixedinfectioncausedbymorethanoneserotypeofU.urealyticumincreasedfromphysicalcheck-upgroup(8.6%)toSTIoutpatients(12.4%)tosexworkers(23.9%)(P<0.01).(5)Thereisnostatisticallysignificantdifferenceinthedistributionofserotype1,3,and6ofbiovar1amongthesethreegroups(P=0.763).(6)ThePCRmethoddescribedhereisrelativelysimple,rapidandspecificforthebiotypingandserotypingofbiovar1ofU.urealyticum.Conclusion:Weshouldpaymoreattentiontobiovar2andmixedinfectionsofU.urealyticumthansingleinfectionofbiovar1inclinicpractice.PCRisagoodmethodforbiotypingandserotyping.
机构地区 不详
出版日期 2002年04月14日(中国期刊网平台首次上网日期,不代表论文的发表时间)
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