Cloning and identification of apoptosis specific DNase inhibitor IXAD in Xenopus egg extract-中国期刊网

摘要 XADisanapoptosisspecificDNaseinXenopusandcancutthelinker-DNAbetweennucleosomesduringapoptosisinXenopuslaeviseggextractinducedbycytochromec.XADismostlikelytobethehomologuetoDFF40inhumans.TheactivityofDFF40canbeinhibitedbyDFF45.WereportmolecularcloningandidentificationofanXADinhibitor,IXAD(inhibitorofXAD),inXenopuseggs.WeclonedthecompletecDNAoftheDFF45homologue,IXAD.ThereisaspecificDEVDsequenceinitsN-terminal,whichserves

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Cloning and identification of apoptosis specific DNase inhibitor IXAD in Xenopus egg extract

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Cloning and identification of apoptosis specific DNase inhibitor IXAD in Xenopus egg extract

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