摘要
Allorganisms,rangingfromsingle-celledorganismstohumans,demonstratecircadianrhythmsthatarenear24-hpatternsthatarepresentindependentofenvironmentalcues.Disruptionofthisprocess,calledcircadianmisalignment,isassociatedwithdeleterioushealthoutcomes.Themostextremeexampleofthismisalignmentisshiftwork,andthereisevidencesuggestingastrongassociationbetweenshiftworkandcertaincardiovascularoutcomes.Theoutcomesofmoststudiesincludeobesity,metabolicsyndrome,hypertension,type2diabetesmellitus,atrialfibrillation,andcardiovascularevents.Inthisarticlewereviewthecurrentliteraturewithanemphasisonwomen’scardiovascularhealth.Thedataareconflicting,andthereisapaucityofrobustevidencewithregardtowomen’scardiovascularhealthandcircadianmisalignment.Morestudiesareneededtobetterdelineatethesexdifferencesaswellasthepathophysiologyoftheassociationsbetweencircadianmisalignmentandcardiovasculardiseasessothatwecanprovidepatientswithmorepersonalizedcare.
出版日期
2019年05月25日（中国期刊网平台首次上网日期，不代表论文的发表时间）
