摘要
Theaimofthismanuscriptistoreviewtheactionandadverseeffectsofcombinedoralcontraceptives(COCs)onoculartissues.Thepercentageofunwantedpregnanciesandthesubsequentabortionsmakecontraceptioncrucialworldwide.Over100millionwomenaroundtheworldusecommoncontraceptivemethods,includingintrauterinedevices,combinedestrogenandprogestinoralcontraceptives,aswellasprogestinonlypreparations(oralcontraceptives,implantsorinjections).COCsarewidelyusedforcontraception,buttheyarealsoindicatedinmenorrhagia,endometriosis,acneandhirsutism,fibroiduterusandpremenstrualsyndrome.However,theyhavebeenassociatedwithhighratesofcardiovascularevents,venousthromboembolicdisease,ischemicstrokesandbreastcancer.TheincidenceofCOCs-relatedocularcomplicationsisestimatedtobe1in230000,includingdryeyesymptoms,cornealedema,lensopacitiesandretinalneuro-ophthalmologicorvascularcomplications.WemayinferthattheseriousocularcomplicationsofCOCscanbepreventedbyeliminatingtheestrogendosageandchoosingthird-generationprogestins.Inanycase,doctorsshouldtakeintoconsiderationthesystemicandocularhistoryofthepatientsbeforeselectinganymethodofcontraception.
出版日期
2017年10月20日（中国期刊网平台首次上网日期，不代表论文的发表时间）
