摘要
Nine5-aryl-2-methyloxazolederivativesweresynthesizedviagold-catalyzedalkyneoxidation.AllofthecompoundshavebeenscreenedfortheirantiproliferativeactivitiesagainstMCF-7cell(humanbreastcarcinoma),A549cell(humanlungcarcinoma)andHelacell(humancervicalcarcinoma)linesinvitro.Theresultsrevealedthatcompounds1b,1cand1dexhibitedstronginhibitoryactivitiesagainsttheMCF-7celllines(withIC50valuesof4.6,9.7and2.2mmol/L,respectively).
出版日期
2013年12月22日(中国期刊网平台首次上网日期,不代表论文的发表时间)