Gold-catalyzed oxazoles synthesis and their relevant antiproliferative activities

在线阅读 下载PDF 导出详情
摘要 Nine5-aryl-2-methyloxazolederivativesweresynthesizedviagold-catalyzedalkyneoxidation.AllofthecompoundshavebeenscreenedfortheirantiproliferativeactivitiesagainstMCF-7cell(humanbreastcarcinoma),A549cell(humanlungcarcinoma)andHelacell(humancervicalcarcinoma)linesinvitro.Theresultsrevealedthatcompounds1b,1cand1dexhibitedstronginhibitoryactivitiesagainsttheMCF-7celllines(withIC50valuesof4.6,9.7and2.2mmol/L,respectively).
机构地区 不详
出版日期 2013年12月22日(中国期刊网平台首次上网日期,不代表论文的发表时间)
  • 相关文献