A New Equation for Solute Retention in Liquid Chromatography

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摘要 Inconsiderationoftheadsorptionofsolvent,diluentandsolutemoleculesonthesurfaceofastationaryphase,anewequationforsoluteretentioninliquidchromatographyispresented.Thisequationincludesthreeparameters:thedisplacementequilibriumconstant(Ksd)betweenthesolventanddiluentmoleculesonthesurfaceofthestationaryphase,thetotalnumber(N)ofthesolventanddiluentmoleculesreleasedfromthestationaryphaseafteronesolutemoleculebeingadsorbed,andtheparameter(I)relatedtothethermodynamicequilibriumconstantforthesoluteadsorptiononthestationaryphase.Overthewholeconcentrationrangeofthesolventinthemobilephase,theexperimentalretentiondatacanbewelldescribedbythisequation,parametersKsd,NandIcanbeobtainedbytheregressionanalysisoftheexperimentalretentiondata,andconsequentlythenumberofthesolventandthediluentmoleculesdisplacedbyonesolutemoleculefromthestationaryphasecanalsobederivedatdifferentsolventconcentrationsinthemobilephase.
机构地区 不详
出版日期 2004年03月13日(中国期刊网平台首次上网日期,不代表论文的发表时间)
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