摘要
Inconsiderationoftheadsorptionofsolvent,diluentandsolutemoleculesonthesurfaceofastationaryphase,anewequationforsoluteretentioninliquidchromatographyispresented.Thisequationincludesthreeparameters:thedisplacementequilibriumconstant(Ksd)betweenthesolventanddiluentmoleculesonthesurfaceofthestationaryphase,thetotalnumber(N)ofthesolventanddiluentmoleculesreleasedfromthestationaryphaseafteronesolutemoleculebeingadsorbed,andtheparameter(I)relatedtothethermodynamicequilibriumconstantforthesoluteadsorptiononthestationaryphase.Overthewholeconcentrationrangeofthesolventinthemobilephase,theexperimentalretentiondatacanbewelldescribedbythisequation,parametersKsd,NandIcanbeobtainedbytheregressionanalysisoftheexperimentalretentiondata,andconsequentlythenumberofthesolventandthediluentmoleculesdisplacedbyonesolutemoleculefromthestationaryphasecanalsobederivedatdifferentsolventconcentrationsinthemobilephase.
出版日期
2004年03月13日(中国期刊网平台首次上网日期,不代表论文的发表时间)