Distribution and Accumulation of Neodymium and Its Effect on Secretion of Progesterone in Mice

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摘要 DistributionandaccumulationofNd,anditseffectonsecretionofprogesteroneinmicewerestudiedusingradioisotopetracer(147Nd)technique.Followingsingleintraperitonealadministrationofneodymiumtracedwith147Ndatadoseof200mg*kg-1,unevendistributionoftheradioactiveNdoccurredinvarioustissuesandorgans.Muchamountof147Ndaccumulatesinthebone,andtheresidueincreaseswiththelapseoftime.Someamountofradioactivitywasalsodetectedineyes,bloodandbrain,buttheaccumulationdecreasedwiththetimeduetoexcretionandre-distributioninmice.Incomparisonwithcontrols,concentrationofprogesteroneisfoundtobesignificantlylowerintheserumofadministeredmice,indicatingasignificantlyinhibitoryeffectofNdonsecretionofprogesterone.
机构地区 不详
出版日期 2004年02月12日(中国期刊网平台首次上网日期,不代表论文的发表时间)
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