简介：Inthispaper,theresponseoftheatmospheric3-5yearcycletoNorthernPacificSSTisdiscussed,Theresultsareasfollows:1.FromthesimultaneoustemporalcorrelationsbetweentheEquatorialEasternPacificSST,thewesterlydirftarea’sSSTandtheNorthernPacificSSTatallgridpoints,wefindthattherearethreecorrelativeregionsintheNorthernPacificSSTfield,theyarethewesterlydriftarea,theEquatorialEasternPacificandtheAlaskaBay,andtheirstructuresareverysimilartothePNApatternintheatmosphereThedifferencePTIbetweentheEquatorialEasternPacificSSTanomalyandthewesterlydriftarea’sSSTanomalycanindicatethechangeofthePNApatternoftheNorthernPacificSSTanomaly.ItcanrepresentSSTchangeof65%areasovertheNorthernPacificandcankeepwatchonElNinoandun-ElNino.2.SimultaneoustemporalcorrelativefieldbetweenPTIandfiltered500hPa(thereis3-5yearcycleonly)oftheNorthernHemispherepresentsclearPNAstructure.Theresp

简介：这份报纸证明一个环形的模式能从北方大西洋摆动(NAO)和Pacific/North美国人(PNA)的联合被构造模式。伪环状，南方的偶极子和构造环形的模式的垂直barotropy大西洋摆动(AO)模式类似于那些。它也以变化贡献是一个主导的模式。而且，它与AO的时间的关联是相当强壮的。这个新环形的模式优于AO因为它合并PNA的大部分并且做行动的中心在和平更强壮、比AO的更身体上相关。或，更通常，它可以被认为是不同于AO的一个物理模式。这研究的结果也显示NAO-PNA观点包含大多数AO的信息，而AO观点仅仅关于NAO-PNA的信息的一半包含。因而，NAO-PNA观点被作者考虑比AO的更全面。

简介：Peptidenucleicacids(PNAs)aresyntheticoligonucleotideswithchemicallymodifiedbackbones.PNAscanbindtobothDNAandRNAtargetsinasequence-specificmannertoformPNA/DNAandPNA/RNAduplexstructures.Whenboundtodouble-strandedDNA(dsDNA)targets,thePNAmoleculereplacesoneDNAstrandintheduplexbystrandinvasiontoformaPNA/DNA/PNA[or(PNA)2/DNA]triplexstructureandthedisplacedDNAstrandexistsasasinglestrandedD-loop.PNAhasbeenusedinmanystudiesasresearchtoolsforgeneregulationandgenetargeting.TheDloopsgeneratedfromthePNAbindinghavealsobeendemonstratedforitspotentialininitiatingtranscriptionandinducinggeneexpression.PNAprovidesapowerfultooltostudythemechanismoftranscriptionandaninnovativestrategytoregulatetargetgeneexpression.AnunderstandingofthePNA-mediatedgeneregulationwillhaveimportantclinicalimplicationsintreatmentofmanyhumandiseasesincludinggenetic,cancerous,andage-relateddiseases.