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  • 简介:SighfertilitylevelinTibetZhangTianluDatafromthe1982and1990censusesinTibetshowthebirthrateinTibetandinaltheprefecturesoftheReg...

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  • 简介:AbstractTraditional radiotherapy and chemotherapy often cause irreversible damage to the fertility and endocrine function of cancer patients. The current methods of fertility preservation include freezing the sperms of adult and adolescent males after puberty; freezing the embryos, oocytes, and ovarian tissue of females; and drug intervention and fertility preservation surgery. This article reviews fertility preservation in cancer patients with respect to current methods, indications, and some more recently developed methods that remain under investigation.

  • 标签: Cryopreservation of Ovarian Tissue Cryopreservation of Testis Tissue Cryopreserved Embryos and Oocytes Fertility Preservation In vitro Maturation
  • 简介:ExaminingChina'spopulationchangesinthepastthreedecadesdemonstratesthatChina'sdemographictransitionhasbeensuccessfullycompletedwithasplendidandzigzagpath.Thereareprofoundhistoricalexperiencesandlessons.ThispaperreviewsChina'sfertilitytransitionwhichisdividedintofourperiodsandarguesthatfertilitychangesarearesultoftheinteractionsbetweensocioeconomicdevelopment,fertilitybehaviorsandfertilitypolicies.Substantialresistancetothe'one-childpolicy'during1979to1984resultedinreboundingandfluctuatingfertility.Thebabyboomoccurredintheperiod1985to1991wasamanifestationoftheinherentlawsofdemographicdynamics,andsubsequentlyforcefulbirthcontrolwasagainmobilized.Theperiodfrom1992to1999witnessedlargedeclinesinfertilitywhichpenetratesthereplacementzone,showingthatChinawascompletingthefertilitytransition.China'sstabilizinglowfertilityandemergingpopulationstructuralissuessince2000callforcomprehensivewaysinaddressingthepopulationproblems.

  • 标签: 生育率 中国 课程 人口变化 人口结构 历史经验
  • 简介:Oftenthelifecycledataoccurascountofthevitaleventsandarerecordedasintegers.Thepurposeofthisarticleistomodelthefertilitybehaviorbasedonreligious,educational,economic,andoccupationalcharacteristics.TheresponsesofclassifiedgroupsaccordingtothesedeterminantsareexaminedforsignificantinfluenceonfertilityusingPoissonregressionmodel(PRM)basedontheNationalFamilyHealthSurvey-3dataset.TheobservedandpredictedprobabilitiesunderPRMindicatemodalvalueoftwochildrenforthePoissondistributionmodeleddata.Presenceofdominanceoftwochildinthedatamotivatestheauthorstoadoptmultinomialregressionmodel(MRM)inordertolinkfertilitywithvarioussocioeconomicindicatorsresponsibleforfertilityvariation.Choiceoftheexplanatoryfactorsislimitedtotheavailabilityofdata.Trendsandpatternsofpreferenceforbirthcountssuggestthatreligion,caste,wealth,femaleeducation,andoccupationarethedominantfactorsshapingtheobservedbirthprocess.Empiricalanalysissuggeststhatboththemodelsusedinthestudyperformsimilarlyonthesampledata.However,fittingofMRMbytakingbirthcountoftwoascomparisoncategoryshowsimprovedAkaikeinformationcriterionandconsistentAkaikeinformationcriterionvalues.CurrentworkcontributestotheexistingliteratureasitattemptstoprovidemoreinsightintothedeterminantsofIndianfertilityusingPoissonandMRM.

  • 标签: COUNT data FERTILITY POISSON model MULTINOMIAL
  • 简介:AbstractThe source of human oocytes is directly associated with the success of infertility treatment and fertility preservation. The number of oocytes obtained is possibly correlated with the success rate in terms of live birth rates. However, oocyte quality must be refined such that the number of oocytes is not positively correlated with the quality of oocytes. Different ovarian stimulation protocols can be used to obtain numerous oocytes. However, oocyte quality should be considered the most important factor affecting infertility treatment and fertility preservation. Infertile women are generally willing to take health-related risks to achieve a live birth, and ovarian stimulation using high-dose hormonal treatments may be harmful for both women and infants. Therefore, successful infertility treatment and fertility preservation should be defined as the birth of a healthy baby at term without compromising the health and safety of the mother and infant. Therefore, the source of high-quality oocytes must be carefully considered prior to infertility treatment and fertility preservation.

  • 标签: Oocytes Infertility Fertility preservation Ovarian stimulation Live birth
  • 简介:FertilityDeclineandPopulationGrowth:China'sDilemmaChinahasatpresentapopulationofover1.2billion,whichismorethanthepopulationof...

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  • 简介:AbstractMany female fertility preservation-related technologies have recently been developed in response to increasing demand for such treatments. To establish standard practices of female fertility preservation in China, the Chinese Maternal and Child Health Association Affiliated Fertility Preservation Professional Committee assembled specialists to construct a consensus, referring to the current clinical guidelines of some countries combined with clinical practice and expert opinions. The consensus includes two parts: (1) indications for female fertility preservation and related techniques, in which we sought to be inclusive regarding the indications for fertility preservation; and (2) practical guidance for the clinical application of the female fertility preservation technologies.

  • 标签: Fertility preservation Neoplasms Reproductive techniques Assisted Oocyte cryopreservation Ovarian tissue cryopreservation
  • 简介:精子chromatin/DNA正直为父亲的基因信息的精确传播是必要的,并且正常精子染色质结构为使肥沃的精子是重要的能力。精液的常规检查,包括精子集中,活动性和形态学,不在精子染色质结构识别缺点。为它的评价的精子DNA损坏和许多方法的起源被描述。精子DNA损坏的评估看起来是为估计男富饶潜力的一个有用工具在活体内和在试管内。后代上的精子DNA缺点的可能的影响也被讨论。

  • 标签: 精子质量 染色体 男性 生育能力 生物学
  • 简介:植物荷尔蒙植物生长素在调整植物生长和开发起一个关键作用。最近的进展在植物生长素反应小径的理解被做了,首先由在Arabidopsis的植物生长素反应异种的描述。另外,microRNAs(miRNAs)被显示了是为正常植物开发和生理学重要的基因的批评管理者。然而,很少对在miRNAs并且在正常开发期间的神经质的发信号之间的可能的相互作用被知道。这里,我们显示出那ArabidopsismicroRNA,miR167,有一个互补序列到AUXIN反应FACTOR6(ARF6)和ARF8mRNAs的部分,能为ARF8,然而并非为ARF6引起抄本降级。我们报导35S::MIR167b的phenotypic描述转基因的线,和表演转基因的线有的那严重35S::MIR167barf6arf8的类似于那些的显型加倍异种。转基因的显型建议miR167可以镇压在翻译的水平的ARF6。我们证明转基因的植物在花的机关的所有四锭盘是有缺点的。在转基因的花,细丝是反常地短的,花药不能适当地释放花粉,并且花粉谷物没发芽。我们的结果提供在表明网络支持的基因表示和植物生长素的调停miRNA的规章的小径之间的一个重要连接种繁殖开发。

  • 标签: 植物 繁殖能力 RNA167 激素 生长
  • 简介:AbstractPlacenta accreta spectrum is a complication of pregnancy, which poses a great risk on maternal health. Historically, hysterectomy was the modality of treatment of such condition, but an approach towards a more conservative management has been in the light recently. This includes several methods with varying rates of success and complications. Expectant management is effective in up to 78%-80% of the cases. The extirpative method is associated with a high risk of postpartum hemorrhage. The success of the one-step conservative procedure depends on the degree of placental invasion, and the triple-P procedure appears to be successful but requires and interdisciplinary approach. Adjuvant treatment options can be tailored according to individual cases, and these include methotrexate injection, uterine devascularization and hysteroscopic resection of retained placental tissues. Follow up after conservative management is crucial to detect complications early, and it can be done by ultrasound, Doppler examination, and trending β human chorionic gonadotropin levels. Conservative management of placenta accreta spectrum can preserve future fertility but should only be done in hospitals with enough experience as it carries a high risk of maternal complications. In the future, more research should be directed to achieve clear guidelines regarding this topic.

  • 标签: Placenta accreta Conservative management Maternal morbidity Fertility outcomes
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  • 简介:AbstractThere is currently no universally accepted unified diagnostic standard for infertility treatment and maternity protection related to polycystic ovary syndrome (PCOS) worldwide, and the treatment options vary greatly. To improve the understanding of PCOS-related infertility among Chinese obstetricians and gynecologists at all levels for better patient diagnosis and management, we have referred to the international expert recommendations and literature and taken into account the Chinese clinical practice to develop the "Consensus on infertility management and fertility preservation related to PCOS."

  • 标签: Diagnosis and Treatment Expert Consensus Fertility Protection Infertility Treatment Polycystic Ovary Syndrome
  • 简介:Seventeenricevarietiesandhybridsofdifferenttypes(indica,japonica,javanica,indicahybrid,japonicahybridandinter-subspecifichybrid)wereevaluatedtodeterminetheeffectoftemperatureonpollenfertilityininter-subspecfichybrids.Thepollenfertilityofinter-subspecifichybridswasgreatlyreducedwhenaveragedailytemperaturedroppedto22.0-23.0℃atmeiosisstage,andtheextentofpollenfertilityreductionvariedgreatlywithrespecttodifferenthybrids.However,thepollenfertilityreductionofindicaandjaponicahybridsandconventionalvarietieswasnotobviousunderthesameregimeoftemperatureconditions.Whentheaveragedailytemperaturedroppedto20℃.thepollendevelopmentofconventionalvarietiesandhybridswasalsoaffected.Correlationanalysisrevealedthatthereexistedapositivecorrelationbetweenpollenfertilityandaveragedailytemperature.Asignificantdifference(P<0.01)wasalsofoundbetweenthetwocorrelationcoefficientsi.e.inter-subspecifichybridsandconventionalvarieties.Temperatureatmeiosisstageofpollenmothercellwasakeyfactorinpollendeveloping,andthepollenfertilityofinter-subspecifichybridswasmoresensitivetolowtemperaturethanthatoftraditionalvariety.

  • 标签: 亚种间杂交 水稻 温度 花粉育性 日平均温度 减数分裂时期
  • 简介:LiJianmin,PhDofeconomics,bornin1955,currentlyisprofessorinPopulationandDevelopmentInstituteofNankaiUniversity,VicePresidentofChinaPopulationAssociation,andmemberofExpertCommitteeofNationalPopulationandFamilyPlanningCommission.HeusedtobeheadofPopulationandDevelopmentInstituteofNankaiUniversityfrom1993to2004.HehasundertakenmanyimportantresearchprogramsofNationalSocialScienceFoundation,NaturalScienceFoundationandKeyResearchInstitutesofHumanitiesandSocialScienceofMinistryofEducation,aswellasthoseof

  • 标签: 中国人口 计划生育 人文社会科学 自然科学基金 专家委员会 南开大学